Description
Snap-8 (Acetyl Octapeptide-3) is a synthetic peptide that is an elongation of the famous Argireline peptide. It is studied for its ability to reduce the appearance of expression wrinkles by modulating muscle contraction. Researchers investigate its mechanism of interfering with the SNARE complex as a potential topical alternative in cosmetic science. This high-purity, lyophilized (powdered) peptide is manufactured for in vitro studies and controlled laboratory analysis only. Each vial undergoes rigorous quality control to ensure consistency in research applications.
What is Snap-8?
Acetyl octapeptide-3, also known as SNAP-8, Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2, Acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-arginyl-alanyl-asparagine, is a 8-amino acid research single peptide. CAS Number: 868844-74-0. Molecular weight: 1073.2 Da. Sequence: Ac-EE-MQ-RR-AD-NH2 (sequence); C42H72N16O15S (formula).
What has Snap-8 been studied for in research?
Analytical method development for quantification in cosmetics via LC-MS/MS Ji et al., Journal of Analytical Science and Technology (2020). Limited published preclinical studies identified. All findings referenced are from preclinical and in vitro studies. No approved clinical applications exist for this research compound.
How should Snap-8 be stored for research use?
-20°C to -80°C in dry, dark conditions for long-term stability of lyophilized form Avoid repeated freeze-thaw cycles. Once reconstituted, the solution should be refrigerated at 2-8°C and used within 28 days.
What is the mechanism of action of Snap-8 in research models?
Mimics N-terminal end of SNAP-25, competes for SNARE complex formation to modulate neurotransmitter exocytosis in cellular models (analogous to related peptides; direct studies primarily on similar hexapeptide) These mechanisms have been characterized in preclinical models only.

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